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Vitamin D3 is an essential nutrient that helps maintain healthy bones and a healthy immune system, as well as supporting overall well-being. Each capsule contains 4000 IU of Vitamin D3 and 100 mcg of K2-MK7.
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National Overview
Even with sunshine, Portugal remains deficient.
Most people in Portugal live below the protective threshold. Vitamin D deficiency is not just a number on a blood test; it may be the root cause of chronic fatigue, low immunity, and bone fragility.
Restore your vitality
Active immune defense
66%
of Portuguese adults are clinically deficient in Vitamin D3.1
Benefits of Vitamin D3 Supplementation
01Emotional Balance Support
Clinical studies indicate that supplementation with Vitamin D3 can contribute to improvements in mood, anxiety and depression in people with insufficient levels. 12
02Effects on Influenza
Vitamin D3 supplementation has been associated with up to a 36% reduction in the risk of developing influenza in several clinical analyses, according to a meta-analysis of 10 randomized controlled trials. 3
03Armored Respiratory System
An analysis of 25 clinical trials involving more than 10,000 participants concluded that Vitamin D supplementation may significantly reduce the risk of respiratory infections. 4
04Vitamin D3 and the Colon
This is probably the field with the strongest scientific evidence in the context of Vitamin D3 and cancer. Several studies suggest that supplementation may be associated with a significant reduction in colon cancer mortality. 56
05Anti-inflammatory Support
Vitamin D3 supplementation has been associated with significant reductions in inflammation levels, according to meta-analyses of clinical trials. 1011
06Headaches and Migraines
Meta-analyses indicate that Vitamin D3 supplementation may be associated with a significant reduction in the frequency and intensity of migraines in people who are deficient in this vitamin. 14
07Health Support and Long Life
Current evidence, based on more than 80 randomized controlled clinical trials, suggests that regular Vitamin D3 supplementation may contribute to a statistically significant reduction in all-cause mortality. 16
What is Vitamin D3?
Vitamin D3 (cholecalciferol) is a unique vitamin synthesized in the skin through sun exposure. Its role is essential, but insufficient sun exposure (especially in winter or when working in an office) makes supplementation a crucial ally for health.
Prevalence of deficiency
PORTUGAL
66% of Portuguese adults are deficient in Vitamin D3. 19
Deficiency66%
EUROPE
40% of Europeans have levels considered insufficient. 20 These levels worsen dramatically during winter due to low sun exposure.
Reference Levels
For robust health, the goal is to remain in the green zone at all times. Levels below 29 ng/mL require immediate attention. 22
Deficiency< 29 ng/mL
32
Ideal Level> 32 ng/mL
The D3 + K2 Synergy
Without K2: The Risk of Calcification
Vitamin D3 increases calcium absorption. Without K2 to guide that calcium, it may be deposited in the arteries (calcification) instead of the bones. 26
With K2: Calcium’s GPS
Vitamin K2 activates proteins that prevent arterial calcification and “bind” calcium to the bones, where it is actually needed. 27
Pay attention to the form of K2
We use the MK7 (Menaquinone-7), which is far superior and more bioavailable than the common MK4 found in generic products. 31
Problems Associated with Vitamin D3 Deficiency
The list of problems associated with Vitamin D3 deficiency is extensive, so levels should always be monitored to ensure adequacy. A deficiency of this vitamin significantly increases the risk of several conditions:
The EFSA (European Food Safety Authority) sets 4,000 IU as the safe daily limit, even for people aged 11 and over. Doses below 10,000 IU/day carry a very low risk of toxicity. 41
RECOMMENDED DAILY DOSE1 Capsule
For optimal absorption, we recommend always taking it with a meal.
Ideal Timing
In the morning or early afternoon. Never on an empty stomach.
Dosage
1 capsule per day.
Always with a fat-rich meal.
I expect it to be a good product. Shame it isn’t encapsulated with a fat-soluble ingredient but with silicon dioxide (even in a small amount, but along with other supplements it can already have some effect). But only after the test results will I be able to give a proper assessment.
INSYGMA NUTRITION
My levels went from 25 to 40 after 2 months. I recommend it 100%
this is the only one I use now my levels went up a bit in 2 months of use
I expect it to be a good product. Shame it isn’t encapsulated with a fat-soluble ingredient but with silicon dioxide (even in a small amount, but along with other supplements it can already have some effect). But only after the test results will I be able to give a proper assessment.
After 2 months of supplementing my levels went up to 55, I really recommend it
I recommend