Benefits of Vitamin D3 Supplementation

Emotional Balance Support

Clinical studies indicate that supplementation with Vitamin D3 can contribute to improvements in mood, anxiety and depression in people with insufficient levels. ^{1 2}

Efeitos na Gripe

Vitamin D3 supplementation has been shown, in several clinical analyses, to be associated with a reduction in the risk of developing influenza by up to 36%, according to a meta-analysis that evaluated 10 randomized and controlled studies, with a total of 4859 participants. ³

Armored Respiratory System

An analysis of 25 clinical trials, with more than 10,000 participants, concluded that supplementation with Vitamin D can significantly reduce the risk of respiratory infections, with effects particularly evident in people with very low levels of this Vitamin. ⁴

Vitamina D3 e o Cólon

This is probably the field with the most scientific evidence in the context of Vitamin D3 and cancer. Several studies suggest that supplementation may be associated with a significant reduction in colon cancer mortality, as well as its development. ^{5 6 7 8 9}

Suporte Anti-inflamatório

Vitamin D3 supplementation has been associated with significant reductions in inflammation levels, according to meta-analyses of clinical trials. This effect is observed in virtually all studies done in this field. ^{10 11 12 13}

Headaches and Migraines

Meta-analyses of randomized clinical trials indicate that vitamin D3 supplementation may be associated with a significant reduction in the frequency and intensity of migraines in individuals with a deficiency of this vitamin. ^{14 15}

Health Support and Long Life

Current evidence, based on more than 80 randomized controlled clinical trials, suggests that regular supplementation with Vitamin D3 may contribute to a statistically significant reduction in all-cause mortality, especially in deficient populations. ¹⁶
Other studies have shown that vitamin D3 supplementation significantly reduced mortality from several cancers. ^{17 18}

O que é Vitamina D3?

Vitamin D3 (cholecalciferol) is a unique vitamin, synthesized in our skin through exposure to sunlight. Its role in the body is fundamental. However, many people do not get enough sun exposure, especially those living in low-light regions or spending most of their time indoors. In such cases, supplementation becomes a valuable ally.

Prevalence of Vitamin D3 Deficiency

A study carried out in Portugal showed that 66% of Portuguese adults were deficient in Vitamin D3. ¹⁹
Studies in the European population show that there is an epidemic of Vitamin D3 deficiency, with 401% of Europeans having Vitamin D3 levels that are considered insufficient ²⁰. These values are more prevalent in winter, due to the absence of sunlight.

Optimal Levels and Deficiency of Vitamin D3

Deficiency is considered when levels are below 29 ng/mL (75nmol/L). ²¹
Adequate levels range from 32ng/mL to 100ng/mL (80nmol/L-250nmol/L). ²²

Why Combine Vitamin D3 with Vitamin K2?

Vitamin D3 increases the absorption of calcium in the intestines, this in high amounts can cause hypercalcemia ^{23 24 25}, which is excess calcium in the bloodstream, especially when combined with calcium intake, this process can lead to arterial calcification ²⁶.
Vitamin K2, being a strong inhibitor of arterial calcification, prevents this process from occurring. It also directs excess calcium to the bones. ^{27 28}
Vitamin K2 has been shown to reduce markers of calcification in controlled studies. ^{29 30}

Importance of the Form of Vitamin K2

Not all forms of Vitamin K2 are equally bioavailable, so you need to be careful when reading the label to know exactly which form of K2 is present.
Vitamin K2 MK4 is much inferior and has no effect on Vitamin K2 levels when compared to the MK7 form, which is what we use in our product. ³¹

Problems Associated with Vitamin D3 Deficiency

The list of problems associated with Vitamin D3 deficiency is vast, levels should always be monitored to ensure adequate levels.
A deficiency in this vitamin increases the risk of bone fractures. ³², chronic kidney disease ³³, diabetes ³⁴, multiple sclerosis ³⁵, mortality ³⁶, rickets ³⁷, osteoporosis ³⁸, depression ³⁹ and much more.

Is the Vitamin D3 dosage in this product safe?

The EFSA (European Food Safety Authority) has determined 4,000 IU as the acceptable limit, even for children over 11 years old. ⁴⁰
Doses below 10,000 IU per day pose a very low risk of developing Vitamin D3 toxicity. ⁴¹

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